Product Note: DMEM Low Glucose (1.0 g/L) with L-Glutamine, Sodium Pyruvate & Pyridoxine HCl
Key Considerations for Use:
L-Glutamine Stability: This formulation contains L-glutamine, which may degrade over time. We recommend:
✓ Regularly checking the expiration date
✓ Monitoring medium performance
✓ Supplementing with fresh L-glutamine if extended culture periods are requiredSterile Technique:
✓ Always use aseptic techniques during preparation and handling
✓ Work in a laminar flow hood when possible
✓ Filter supplements if added post-thawStandard Supplementation:
✓ Typically supplemented with 5-10% FBS (fetal bovine serum) for essential growth factors and nutrients
✓ May require additional components depending on cell type:
• Antibiotics (e.g., penicillin/streptomycin)
• Non-essential amino acids
• Cell-specific growth factors
Product Overview:
DMEM Low Glucose (1.0 g/L) is a versatile basal medium optimized for:
✓ Primary cell cultures (neurons, hepatocytes, etc.)
✓ Glucose-sensitive applications (metabolic studies, differentiation protocols)
✓ Research requiring controlled glucose conditions (diabetes studies, signaling pathway analysis)
Storage & Handling Protocol:
Temperature: Maintain at 2-8°C (do not freeze)
Light Protection: Store in original packaging
Shelf Life: Use before expiration date on label
Thawing: If frozen supplements are added, warm gradually to 37°C
Experimental Flexibility:
This formulation serves as an excellent base medium that can be customized with various supplements to meet specific research requirements, making it invaluable for:
• Metabolic studies
• Stem cell differentiation
• Specialized cell culture applications